Formula Breakdown
Citrulline Malate is one of the most common ingredients found in preworkouts, for a good reason. It can decrease muscle soreness 24 hours after training by up to 40% [1], increase ATP production during exercise by up to 34% [2], and increase flow mediated dilation (FMD) by 34% [3]. This results in enhanced recovery, improved performance, and a better pump in the gym.
Betaine Anhydrous, not to be confused with Beta Alanine, has various benefits. Betaine has been shown to significantly increase the anabolic environment within the body. While this may sound like "Bro Science", there is actually research to support the claim [4]. This study showed an increase in IGF-1 (growth hormone), and a decrease in cortisol levels (stress hormone). Another study concluded that body composition, muscle size, work volume, and power were all improved with Betaine supplementation [8].
Nitrosigine is a patented complex of bonded arginine silicate. Arginine is an amino acid that increases nitric oxide levels (pump) in the gym, but arginine alone does not increase blood arginine efficiently due to poor bioavailability. Nitrosigine fixes this issue, making it a great candidate for a nitric oxide booster [9]. In the same study that found Citrulline Malate increased FMD by 34%, it found that Nitrosigine increased FDM by 31% [2]. Stacking these ingredients will maximize nitric oxide levels, giving you a fantastic pump. Additionally, Nitrosigine has been proven to increase focus and cognition [10].
Agmatine Sulfate is another ingredient included to increase your pump in the gym. Agmatine increases nitric oxide in a unique way; through the endothelial nitric oxide synthase isoform, also known as eNOS. eNOS accelerates vasodilation and increases blood flow, while agmatine increases eNOS [11]. Agmatine is also a neural protectant [12], so it can facilitate the feeling of hyperfocus or being "locked in" [13]. A combination of these first four ingredients will deliver an extraordinary pump that other preworkouts simply can't compete with.
Alpha GPC is a natural choline compound found in the brain, considered to be a vital nutrient [14]. Choline is potentially one of the most effective nootropics out there, making it great for preworkout supplementation. This is because of its ability to release the neurotransmitter acetylcholine and increase intracellular communication, which could result in great power and force output [15], [16]. Alpha-GPC also has potential neuroprotective [17] and cognitive enhancing properties [18], [19].
Caffeine. We all know and love it. Some benefits include cancelling out any loss in performance due to sleep deprivation [20] and improving mood and feelings of euphoria [21] [22]. It has also shown to reduce perception of pain [23] and increase exercise performance overall [24] [25]. At the end of the day, Serpent (and any other stimulant preworkouts) would not be nearly as effective without it. With a hard-hitting 275mg dose, you'll be sure to feel all the benefits.
Dynamine and Caffeine are like Batman and Robin. Dynamine, a patented stimulant, increases the half life of caffeine, preventing that dreaded “crash” you may feel after taking other products with caffeine [26]. It also reduces the anxiety and jitters that may be associated with caffeine. Dynamine is fast acting and delivers high-impact energy, mood, motivation, and focus. It also has additional benefits when stacked with TeaCrine (explained in the TeaCrine section).
Rhodiola Rosea is an adaptogenic nootropic used to stimulate the nervous system, reduce anxiety, enhance performance, and relieve fatigue. After taking Serpent you will notice a distinct wave of focus hit you after about 15 minutes, which are the effects of Rhodiola Rosea. Rhodiola Rosea fights off metal fatigue in stressful situations [32] [33] [34] [35]. It also can improve overall mood while reducing anxiety, stress, and anger [36] [37]. We choose RhodioLife because of its unique “fingerprint” composition. With Rhodiolife, not only is the percentage of the primary actives (rosavins, rosarins, rosins and salidrosides) the same as the root, but so is the ratio of actives. This is not the case with many other Rhodiola Rosea products, making RhodioLife a great addition to the formula.
ElevATP is a patented blend of ancient peat and apple extract. ElevATP does exactly what the name suggests; it elevates ATP levels within the body. This results in an increase of peak power and force, [39] and an increase in cellular energy, which will improve endurance. ElevATP aids in improving lean muscle mass and strength while also increasing power output and training volume.
TeaCrine is a patented stimulant containing a chemically equivalent bioactive version of theacrine. Theacrine is a naturally occurring ingredient similar to caffeine, found in teas and coffee. TeaCrine delivers clean, long-lasting energy. It also improves mood, motivation and focus [40], [41], [42], [43]. The results of TeaCrine are best when stacked with both Dynamine and Caffeine. Teacrine is safe and non habituating [41], and similar to Dynamine, there is no crash or jitters. The combination of Caffeine, Dynamine, and TeaCrine delivers a unique energy boost like no other.
Ginkgo Biloba is another effective nootropic. It has been shown to increase muscle tissue blood flow, making it yet another pump enhancing ingredient [42]. Some other benefits include reduced cortisol under stressful situations [43] and an improvement in cognitive function [44]. The cognitive benefits are the main reason it is included in the formula. Supplementation has shown a myriad of cognitive benefits including improved memory, speed, and focus [45] [46] [47]. This is another unique ingredient that you won't find in many other preworkouts.
Astragin is a patented compound that increases absorption of many vital nutrients and promotes a healthy gut environment. It has been shown to increase the steady-state absorption rate of arginine, agmatine and citrulline, by 67%, 36% and 45%, respectively [48]. It has also been shown to promote gut health, immune function, and nutritional profile and increase ATP production by up to 18%.